Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Matrix-assisted laser desorption/ionization time-of-flight (MALDI TOF) mass spectrometry has become a promising alternative for high-throughput drug discovery as new instruments offer high speed, flexibility and sensitivity, and the ability to measure physiological substrates label free. Here we dev...

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Detalles Bibliográficos
Autores principales: Heap, Rachel E., Hope, Anthony G., Pearson, Lesley-Anne, Reyskens, Kathleen M. S. E., McElroy, Stuart P., Hastie, C. James, Porter, David W., Arthur, J. Simon C., Gray, David W., Trost, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700774/
https://www.ncbi.nlm.nih.gov/pubmed/28692323
http://dx.doi.org/10.1177/2472555217717473

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