AQ-13, an investigational antimalarial, versus artemether plus lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria: a randomised, phase 2, non-inferiority clinical trial

BACKGROUND: Chloroquine was used for malaria treatment until resistant Plasmodium falciparum was identified. Because 4-aminoquinolines with modified side chains, such as AQ-13, are active against resistant parasites, we compared AQ-13 against artemether plus lumefantrine for treatment of uncomplicat...

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Detalles Bibliográficos
Autores principales: Koita, Ousmane A, Sangaré, Lansana, Miller, Haiyan D, Sissako, Aliou, Coulibaly, Moctar, Thompson, Trevor A, Fongoro, Saharé, Diarra, Youssouf, Ba, Mamadou, Maiga, Ababacar, Diallo, Boubakar, Mushatt, David M, Mather, Frances J, Shaffer, Jeffrey G, Anwar, Asif H, Krogstad, Donald J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700806/
https://www.ncbi.nlm.nih.gov/pubmed/28916443
http://dx.doi.org/10.1016/S1473-3099(17)30365-1

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