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SN38-PEG-PLGA-verapamil nanoparticles inhibit proliferation and downregulate drug transporter ABCG2 gene expression in colorectal cancer cells

Nowadays, nanoparticle-based drug delivery systems are recognized to reduce the therapeutic side effects. One of the common problems in cancer treatment is cancer drug resistance, resulting from the over-expression of one energy-dependent transporter that enhances drug efflux. Irinotecan is used for...

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Detalles Bibliográficos
Autores principales: Nagheh, Zahra, Irani, Shiva, Mirfakhraie, Reza, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700907/
https://www.ncbi.nlm.nih.gov/pubmed/28948511
http://dx.doi.org/10.1007/s40204-017-0073-y

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