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PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome
Fibrosis of the subsynovial connective tissue (SSCT) is a pathognomonic change in carpal tunnel syndrome (CTS). Identification of molecular targets and anti-fibrotic therapies could provide new treatment strategies for CTS. The contribution of SSCT cells to fibrosis and the signaling pathways that i...
Autores principales: | Saito, Yuki, Chikenji, Takako, Ozasa, Yasuhiro, Fujimiya, Mineko, Yamashita, Toshihiko, Gingery, Anne, Iba, Kousuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700922/ https://www.ncbi.nlm.nih.gov/pubmed/29170419 http://dx.doi.org/10.1038/s41598-017-16443-w |
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