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Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

Growing evidence suggests that agonists of glucagon-like peptide (GLP-1) receptor exert neuroprotective and neurorestorative effects across a range of experimental models of neuronal degeneration, and, recently, a pilot clinical trial of Liraglutide in Alzheimer’s disease patients showed improvement...

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Detalles Bibliográficos
Autores principales: Panagaki, Theodora, Michael, Maria, Hölscher, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700973/
https://www.ncbi.nlm.nih.gov/pubmed/29170452
http://dx.doi.org/10.1038/s41598-017-16488-x