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DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but the involvement of DSB repair in PD-L1 expression has not been investigated. Here we show that PD-L1 expression in ca...

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Detalles Bibliográficos
Autores principales:	Sato, Hiro, Niimi, Atsuko, Yasuhara, Takaaki, Permata, Tiara Bunga Mayang, Hagiwara, Yoshihiko, Isono, Mayu, Nuryadi, Endang, Sekine, Ryota, Oike, Takahiro, Kakoti, Sangeeta, Yoshimoto, Yuya, Held, Kathryn D., Suzuki, Yoshiyuki, Kono, Koji, Miyagawa, Kiyoshi, Nakano, Takashi, Shibata, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701012/ https://www.ncbi.nlm.nih.gov/pubmed/29170499 http://dx.doi.org/10.1038/s41467-017-01883-9

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