A New Approach to Deliver Anti-cancer Nanodrugs with Reduced Off-target Toxicities and Improved Efficiency by Temporarily Blunting the Reticuloendothelial System with Intralipid

We have developed a new strategy to temporarily blunt the reticuloendothelial system uptake of nanodrugs, a major challenge for nanodrug delivery and causing off-target toxicities, using an FDA approved nutrition supplement, Intralipid. We have tested our methodology in rats using an experimental pl...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li, Ye, Qing, Lu, Maggie, Chen, Shih-Ta, Tseng, Hsiang-Wen, Lo, Ya-Chin, Ho, Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701028/
https://www.ncbi.nlm.nih.gov/pubmed/29170482
http://dx.doi.org/10.1038/s41598-017-16293-6

Ejemplares similares

Ejemplares similares