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Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer

The majority of long noncoding RNAs (lncRNAs) is still poorly characterized with respect to function, interactions with protein-coding genes, and mechanisms that regulate their expression. As for protein-coding RNAs, epigenetic deregulation of lncRNA expression by alterations in DNA methylation migh...

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Detalles Bibliográficos
Autores principales: Heilmann, K, Toth, R, Bossmann, C, Klimo, K, Plass, C, Gerhauser, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701091/
https://www.ncbi.nlm.nih.gov/pubmed/28759043
http://dx.doi.org/10.1038/onc.2017.246

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