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Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening

Alzheimer disease and related dementias are major challenges, demanding urgent needs for earliest possible diagnosis to optimize the success rate in finding effective therapeutic interventions. Mounting solid scientific premises point at the core acetylcholine-biosynthesizing cholinergic enzyme, ChA...

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Detalles Bibliográficos
Autores principales:	Kumar, Rajnish, Kumar, Amit, Långström, Bengt, Darreh-Shori, Taher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701137/ https://www.ncbi.nlm.nih.gov/pubmed/29176551 http://dx.doi.org/10.1038/s41598-017-16033-w

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