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Microneedle-array patches loaded with dual mineralized protein/peptide particles for type 2 diabetes therapy
The delivery of therapeutic peptides for diabetes therapy is compromised by short half-lives of drugs with the consequent need for multiple daily injections that reduce patient compliance and increase treatment cost. In this study, we demonstrate a smart exendin-4 (Ex4) delivery device based on micr...
Autores principales: | Chen, Wei, Tian, Rui, Xu, Can, Yung, Bryant C., Wang, Guohao, Liu, Yijing, Ni, Qianqian, Zhang, Fuwu, Zhou, Zijian, Wang, Jingjing, Niu, Gang, Ma, Ying, Fu, Liwu, Chen, Xiaoyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701150/ https://www.ncbi.nlm.nih.gov/pubmed/29176623 http://dx.doi.org/10.1038/s41467-017-01764-1 |
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