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Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences
The current study was designed to explore the epidemiology of extremities chronic osteomyelitis, its prognosis and the complications of the treatment methods being used in southwest China. The data from osteomyelitis patients treated at the Department of Orthopaedics, Southwest Hospital, China betwe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701171/ https://www.ncbi.nlm.nih.gov/pubmed/29176616 http://dx.doi.org/10.1038/s41598-017-16337-x |
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author | Wang, Xiaohua Yu, Shengpeng Sun, Dong Fu, Jingshu Wang, Shulin Huang, Ke Xie, Zhao |
author_facet | Wang, Xiaohua Yu, Shengpeng Sun, Dong Fu, Jingshu Wang, Shulin Huang, Ke Xie, Zhao |
author_sort | Wang, Xiaohua |
collection | PubMed |
description | The current study was designed to explore the epidemiology of extremities chronic osteomyelitis, its prognosis and the complications of the treatment methods being used in southwest China. The data from osteomyelitis patients treated at the Department of Orthopaedics, Southwest Hospital, China between May 2011 and September 2016 were collected and analysed. The study comprised 503 admitted patients, of which 416 males and 87 were females, with an average age of 40.15 ± 5.64 years. Approximately 356 cases were followed for more than 18 months; the average bone union time was 6.24 ± 0.76 months in 94.1% (335) patients, and infections were almost controlled in 93.8% patients. The rate of infection control with the induced membrane technique was higher than with the I-stage free bone graft. Iliac infection was the main complication of the induced membrane technique, and impaired joint activity was the main complication of I-stage free bone grafts. In southwest China, the incidence of haematogenous osteomyelitis, caused mainly by Staphylococcus aureus, remains very high. The speed of bone defect repair and the rate of infection control with the induced membrane technique were superior to those of I-stage free bone grafts. Internal fixation should be given priority because it offers reduced complications with no increase in the recurrence of infection. |
format | Online Article Text |
id | pubmed-5701171 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-57011712017-11-30 Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences Wang, Xiaohua Yu, Shengpeng Sun, Dong Fu, Jingshu Wang, Shulin Huang, Ke Xie, Zhao Sci Rep Article The current study was designed to explore the epidemiology of extremities chronic osteomyelitis, its prognosis and the complications of the treatment methods being used in southwest China. The data from osteomyelitis patients treated at the Department of Orthopaedics, Southwest Hospital, China between May 2011 and September 2016 were collected and analysed. The study comprised 503 admitted patients, of which 416 males and 87 were females, with an average age of 40.15 ± 5.64 years. Approximately 356 cases were followed for more than 18 months; the average bone union time was 6.24 ± 0.76 months in 94.1% (335) patients, and infections were almost controlled in 93.8% patients. The rate of infection control with the induced membrane technique was higher than with the I-stage free bone graft. Iliac infection was the main complication of the induced membrane technique, and impaired joint activity was the main complication of I-stage free bone grafts. In southwest China, the incidence of haematogenous osteomyelitis, caused mainly by Staphylococcus aureus, remains very high. The speed of bone defect repair and the rate of infection control with the induced membrane technique were superior to those of I-stage free bone grafts. Internal fixation should be given priority because it offers reduced complications with no increase in the recurrence of infection. Nature Publishing Group UK 2017-11-24 /pmc/articles/PMC5701171/ /pubmed/29176616 http://dx.doi.org/10.1038/s41598-017-16337-x Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Wang, Xiaohua Yu, Shengpeng Sun, Dong Fu, Jingshu Wang, Shulin Huang, Ke Xie, Zhao Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title | Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title_full | Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title_fullStr | Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title_full_unstemmed | Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title_short | Current data on extremities chronic osteomyelitis in southwest China: epidemiology, microbiology and therapeutic consequences |
title_sort | current data on extremities chronic osteomyelitis in southwest china: epidemiology, microbiology and therapeutic consequences |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701171/ https://www.ncbi.nlm.nih.gov/pubmed/29176616 http://dx.doi.org/10.1038/s41598-017-16337-x |
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