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Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity
L. pneumophila, an important facultative intracellular bacterium, infects the human lung and environmental protozoa. At least fifteen phospholipases A (PLA) are encoded in its genome. Three of which, namely PlaA, PlaC, and PlaD, belong to the GDSL lipase family abundant in bacteria and higher plants...
Autores principales: | Lang, Christina, Hiller, Miriam, Flieger, Antje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701174/ https://www.ncbi.nlm.nih.gov/pubmed/29176577 http://dx.doi.org/10.1038/s41598-017-12796-4 |
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