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Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity

L. pneumophila, an important facultative intracellular bacterium, infects the human lung and environmental protozoa. At least fifteen phospholipases A (PLA) are encoded in its genome. Three of which, namely PlaA, PlaC, and PlaD, belong to the GDSL lipase family abundant in bacteria and higher plants...

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Detalles Bibliográficos
Autores principales: Lang, Christina, Hiller, Miriam, Flieger, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701174/
https://www.ncbi.nlm.nih.gov/pubmed/29176577
http://dx.doi.org/10.1038/s41598-017-12796-4

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