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Baculovirus-Mediated miR-214 Knockdown Shifts Osteoporotic ASCs Differentiation and Improves Osteoporotic Bone Defects Repair

Osteoporotic patients often suffer from bone fracture but its healing is compromised due to impaired osteogenesis potential of bone marrow-derived mesenchymal stem cells (BMSCs). Here we aimed to exploit adipose-derived stem cells from ovariectomized rats (OVX-ASCs) for bone healing. We unraveled th...

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Detalles Bibliográficos
Autores principales: Li, Kuei-Chang, Chang, Yu-Han, Hsu, Mu-Nung, Lo, Shih-Chun, Li, Wan-Hua, Hu, Yu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701180/
https://www.ncbi.nlm.nih.gov/pubmed/29176755
http://dx.doi.org/10.1038/s41598-017-16547-3