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Quenching protein dynamics interferes with HIV capsid maturation
Maturation of HIV-1 particles encompasses a complex morphological transformation of Gag via an orchestrated series of proteolytic cleavage events. A longstanding question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA–SP1), which represents an intermediate during matur...
Autores principales: | Wang, Mingzhang, Quinn, Caitlin M., Perilla, Juan R., Zhang, Huilan, Shirra Jr., Randall, Hou, Guangjin, Byeon, In-Ja, Suiter, Christopher L., Ablan, Sherimay, Urano, Emiko, Nitz, Theodore J., Aiken, Christopher, Freed, Eric O., Zhang, Peijun, Schulten, Klaus, Gronenborn, Angela M., Polenova, Tatyana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701193/ https://www.ncbi.nlm.nih.gov/pubmed/29176596 http://dx.doi.org/10.1038/s41467-017-01856-y |
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