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In vivo evidence that RBM5 is a tumour suppressor in the lung

Cigarette smoking is undoubtedly a risk factor for lung cancer. Moreover, smokers with genetic mutations on chromosome 3p21.3, a region frequently deleted in cancer and notably in lung cancer, have a dramatically higher risk of aggressive lung cancer. The RNA binding motif 5 (RBM5) is one of the com...

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Detalles Bibliográficos
Autores principales: Jamsai, Duangporn, Watkins, D. Neil, O’Connor, Anne E., Merriner, D. Jo, Gursoy, Selen, Bird, Anthony D., Kumar, Beena, Miller, Alistair, Cole, Timothy J., Jenkins, Brendan J., O’Bryan, Moira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701194/
https://www.ncbi.nlm.nih.gov/pubmed/29176597
http://dx.doi.org/10.1038/s41598-017-15874-9