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Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage

Biological systems often generate unique and useful structures, which can have industrial relevance either as direct components or as an inspiration for biomimetic materials. For fabrication of nanoscale silica structures, we explored the use of the silaffin R5 peptide from Cylindrotheca fusiformis...

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Autores principales: Song, In-Wong, Park, Hyojung, Park, Jung Han, Kim, Hyunook, Kim, Seong Hun, Yi, Sung, Jaworski, Justyn, Sang, Byoung-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701198/
https://www.ncbi.nlm.nih.gov/pubmed/29176625
http://dx.doi.org/10.1038/s41598-017-16278-5
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author Song, In-Wong
Park, Hyojung
Park, Jung Han
Kim, Hyunook
Kim, Seong Hun
Yi, Sung
Jaworski, Justyn
Sang, Byoung-In
author_facet Song, In-Wong
Park, Hyojung
Park, Jung Han
Kim, Hyunook
Kim, Seong Hun
Yi, Sung
Jaworski, Justyn
Sang, Byoung-In
author_sort Song, In-Wong
collection PubMed
description Biological systems often generate unique and useful structures, which can have industrial relevance either as direct components or as an inspiration for biomimetic materials. For fabrication of nanoscale silica structures, we explored the use of the silaffin R5 peptide from Cylindrotheca fusiformis expressed on the surface of the fd bacteriophage. By utilizing the biomineralizing peptide component displayed on the bacteriophage surface, we found that low concentrations (0.09 mg/mL of the R5 bacteriophage, below the concentration range used in other studies) could be used to create silica nanofibers. An additional benefit of this approach is the ability of our R5-displaying phage to form silica materials without the need for supplementary components, such as aminopropyl triethoxysilane, that are typically used in such processes. Because this method for silica formation can occur under mild conditions when implementing our R5 displaying phage system, we may provide a relatively simple, economical, and environmentally friendly process for creating silica nanomaterials.
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spelling pubmed-57011982017-11-30 Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage Song, In-Wong Park, Hyojung Park, Jung Han Kim, Hyunook Kim, Seong Hun Yi, Sung Jaworski, Justyn Sang, Byoung-In Sci Rep Article Biological systems often generate unique and useful structures, which can have industrial relevance either as direct components or as an inspiration for biomimetic materials. For fabrication of nanoscale silica structures, we explored the use of the silaffin R5 peptide from Cylindrotheca fusiformis expressed on the surface of the fd bacteriophage. By utilizing the biomineralizing peptide component displayed on the bacteriophage surface, we found that low concentrations (0.09 mg/mL of the R5 bacteriophage, below the concentration range used in other studies) could be used to create silica nanofibers. An additional benefit of this approach is the ability of our R5-displaying phage to form silica materials without the need for supplementary components, such as aminopropyl triethoxysilane, that are typically used in such processes. Because this method for silica formation can occur under mild conditions when implementing our R5 displaying phage system, we may provide a relatively simple, economical, and environmentally friendly process for creating silica nanomaterials. Nature Publishing Group UK 2017-11-24 /pmc/articles/PMC5701198/ /pubmed/29176625 http://dx.doi.org/10.1038/s41598-017-16278-5 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Song, In-Wong
Park, Hyojung
Park, Jung Han
Kim, Hyunook
Kim, Seong Hun
Yi, Sung
Jaworski, Justyn
Sang, Byoung-In
Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title_full Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title_fullStr Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title_full_unstemmed Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title_short Silica formation with nanofiber morphology via helical display of the silaffin R5 peptide on a filamentous bacteriophage
title_sort silica formation with nanofiber morphology via helical display of the silaffin r5 peptide on a filamentous bacteriophage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701198/
https://www.ncbi.nlm.nih.gov/pubmed/29176625
http://dx.doi.org/10.1038/s41598-017-16278-5
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