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Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer

BACKGROUND: Colorectal cancer is a heterogeneous group of malignancies with complex molecular subtypes. While colon cancer has been widely investigated, studies on rectal cancer are very limited. Here, we performed multi-region whole-exome sequencing and single-cell whole-genome sequencing to examin...

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Detalles Bibliográficos
Autores principales:	Liu, Mingshan, Liu, Yang, Di, Jiabo, Su, Zhe, Yang, Hong, Jiang, Beihai, Wang, Zaozao, Zhuang, Meng, Bai, Fan, Su, Xiangqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701298/ https://www.ncbi.nlm.nih.gov/pubmed/29169336 http://dx.doi.org/10.1186/s12885-017-3777-4

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