Cargando…

Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women

AIM OF THE STUDY: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. MATERIAL AND METHODS: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening...

Descripción completa

Detalles Bibliográficos
Autores principales: Kulhan, Mehmet, Kulhan, Nur G., Seven, Yasemin, Nayki, Umit A., Nayki, Cenk, Ata, Nahit, Ulug, Pasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701576/
https://www.ncbi.nlm.nih.gov/pubmed/29180929
http://dx.doi.org/10.5114/wo.2017.69591
Descripción
Sumario:AIM OF THE STUDY: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. MATERIAL AND METHODS: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening were assessed during the years 2014–2016. Cervical specimens were collected and transported using the HC2 HPV DNA Collection Device (consisting of a cervical brush and digene Specimen Transport Medium). RESULTS: Among these 11 624 individuals, positive HPV test results were obtained for 325 (2.79%), and negative results were observed for 11 299 (97.2%). The vast majority of patients were between the 3(rd) and 5(th) decades and the mean age of the patients was 44 ±9.12 (range 27–66). Among the HPV-positive women, 205 were positive for a single HPV type (205/325 = 63.1% of HPV infections; 205/11624 = 1.76% of all samples) and 120 were positive for multiple types (120/325 = 36.9% of HPV infections; 120/11624 = 1.03% of all samples). The four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively. CONCLUSIONS: There appears to be geographic variation in the distribution of HPV genotypes. In this study, the four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively.