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Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women

AIM OF THE STUDY: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. MATERIAL AND METHODS: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening...

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Autores principales: Kulhan, Mehmet, Kulhan, Nur G., Seven, Yasemin, Nayki, Umit A., Nayki, Cenk, Ata, Nahit, Ulug, Pasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701576/
https://www.ncbi.nlm.nih.gov/pubmed/29180929
http://dx.doi.org/10.5114/wo.2017.69591
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author Kulhan, Mehmet
Kulhan, Nur G.
Seven, Yasemin
Nayki, Umit A.
Nayki, Cenk
Ata, Nahit
Ulug, Pasa
author_facet Kulhan, Mehmet
Kulhan, Nur G.
Seven, Yasemin
Nayki, Umit A.
Nayki, Cenk
Ata, Nahit
Ulug, Pasa
author_sort Kulhan, Mehmet
collection PubMed
description AIM OF THE STUDY: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. MATERIAL AND METHODS: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening were assessed during the years 2014–2016. Cervical specimens were collected and transported using the HC2 HPV DNA Collection Device (consisting of a cervical brush and digene Specimen Transport Medium). RESULTS: Among these 11 624 individuals, positive HPV test results were obtained for 325 (2.79%), and negative results were observed for 11 299 (97.2%). The vast majority of patients were between the 3(rd) and 5(th) decades and the mean age of the patients was 44 ±9.12 (range 27–66). Among the HPV-positive women, 205 were positive for a single HPV type (205/325 = 63.1% of HPV infections; 205/11624 = 1.76% of all samples) and 120 were positive for multiple types (120/325 = 36.9% of HPV infections; 120/11624 = 1.03% of all samples). The four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively. CONCLUSIONS: There appears to be geographic variation in the distribution of HPV genotypes. In this study, the four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively.
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spelling pubmed-57015762017-11-27 Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women Kulhan, Mehmet Kulhan, Nur G. Seven, Yasemin Nayki, Umit A. Nayki, Cenk Ata, Nahit Ulug, Pasa Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. MATERIAL AND METHODS: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening were assessed during the years 2014–2016. Cervical specimens were collected and transported using the HC2 HPV DNA Collection Device (consisting of a cervical brush and digene Specimen Transport Medium). RESULTS: Among these 11 624 individuals, positive HPV test results were obtained for 325 (2.79%), and negative results were observed for 11 299 (97.2%). The vast majority of patients were between the 3(rd) and 5(th) decades and the mean age of the patients was 44 ±9.12 (range 27–66). Among the HPV-positive women, 205 were positive for a single HPV type (205/325 = 63.1% of HPV infections; 205/11624 = 1.76% of all samples) and 120 were positive for multiple types (120/325 = 36.9% of HPV infections; 120/11624 = 1.03% of all samples). The four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively. CONCLUSIONS: There appears to be geographic variation in the distribution of HPV genotypes. In this study, the four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively. Termedia Publishing House 2017-09-29 2017 /pmc/articles/PMC5701576/ /pubmed/29180929 http://dx.doi.org/10.5114/wo.2017.69591 Text en Copyright: © 2017 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Kulhan, Mehmet
Kulhan, Nur G.
Seven, Yasemin
Nayki, Umit A.
Nayki, Cenk
Ata, Nahit
Ulug, Pasa
Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title_full Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title_fullStr Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title_full_unstemmed Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title_short Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish women
title_sort estimation of the prevalence and distribution of hpv genotypes and identification of related risk factors among turkish women
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701576/
https://www.ncbi.nlm.nih.gov/pubmed/29180929
http://dx.doi.org/10.5114/wo.2017.69591
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