Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1)

Hepatitis C virus (HCV) leads to severe liver diseases, including liver fibrosis, cirrhosis and hepatocellular carcinoma. Non-structural protein 3 helicase (NS3h) and non-structural protein 5B RNA-dependent RNA polymerase (NS5B) are involved in the replication of HCV RNA genome, and have been proved...

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Detalles Bibliográficos
Autores principales: Yang, Na, Sun, Chaomin, Zhang, Lixin, Liu, Jianguo, Song, Fuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701637/
https://www.ncbi.nlm.nih.gov/pubmed/29209282
http://dx.doi.org/10.3389/fmicb.2017.02153

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