Loss of peri-Wolffian duct stromal Frs2α expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux

BACKGROUND: Fibroblast growth factor receptor 2 (Fgfr2) deletion from murine peri-Wolffian duct stroma (ST) results in aberrant ureteric bud induction, abnormal ureteral insertion into the bladder, and high rates of vesicoureteral reflux (VUR). It is unclear which receptor docking protein(s) is/are...

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Detalles Bibliográficos
Autores principales: Narla, Deepti, Slagle, Stacey B., Schaefer, Caitlin M., Bushnell, Daniel S., Puri, Pawan, Bates, Carlton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701656/
https://www.ncbi.nlm.nih.gov/pubmed/29135976
http://dx.doi.org/10.1038/pr.2017.175

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