Cargando…

Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas

INTRODUCTION: Activation of the phosphatidylinositol 3-kinase (PI3K)/AKT pathway plays a critical role in carcinogenesis and resistance to anticancer drugs. In this study, gastric carcinomas (GC) were investigated and statistical analyses were performed concerning the correlation between the clinico...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiappini, Paula Blandina Ola, de Medeiros, Ivan Ucella Dantas, Lima, Luiz Guilherme Cenaglia, Fregnani, Jose Humberto, Nonogaki, Suely, da Costa, Wilson Luiz, Coimbra, Felipe Jose Fernandez, Silva, Milton Jose de Barros e, de Mello, Celso Abdon Lopes, Pinto, Clovis Antonio Lopes, Begnami, Maria Dirlei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2016
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701681/ https://www.ncbi.nlm.nih.gov/pubmed/29181056 http://dx.doi.org/10.5114/aoms.2016.60394

Ejemplares similares

Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a single cancer center
por: Costa, Wilson L, et al.
Publicado: (2012)

RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions
por: de Macedo, Mariana Petaccia, et al.
Publicado: (2015)

NDRG1 protein overexpression in malignant thyroid neoplasms
por: Gerhard, Renê, et al.
Publicado: (2010)

Overview of Adult Sarcoma Burden and Clinical Pathways in Brazil
por: David, Bruna Bianca Lopes, et al.
Publicado: (2022)

Safety and preliminary results of perioperative chemotherapy and hyperthermic intraperitoneal chemotherapy (HIPEC) for high-risk gastric cancer patients
por: Costa, Wilson L, et al.
Publicado: (2012)

Gastric Pouch Mixed Adenoneuroendocrine Carcinoma With a Mixed Adenocarcinoma Component After Roux-en-Y Gastric Bypass
por: Pastorello, Ricardo G., et al.
Publicado: (2017)

Hotspot analysis by confocal microscopy can help to differentiate challenging melanocytic skin lesions
por: Castro, Raquel de Paula Ramos, et al.
Publicado: (2022)

Cashew By-Product as a Functional Substrate for the Development of Probiotic Fermented Milk
por: Herkenhoff, Marcos Edgar, et al.
Publicado: (2023)

Combination of ifosfamide and etoposide as a salvage regimen for previously treated soft tissue sarcomas: a retrospective single centre study
por: Ribeiro, Luiz Fernando, et al.
Publicado: (2022)

Evaluation of prognostic factors in stage IIA breast tumors and their correlation with mortality risk
por: Carvalho, Solange Torchia, et al.
Publicado: (2011)

Dihydropyrimidine dehydrogenase (DPD) polymorphisms knocking on the door
por: Donadio, Mauro Daniel Spina, et al.
Publicado: (2022)

Evaluation of prognostic factors in patients undergoing first-line chemotherapy for advanced biliary tract cancer: a retrospective analysis from a South American cancer centre
por: Felismino, Tiago Cordeiro, et al.
Publicado: (2022)

Learning Reflectance Confocal Microscopy of Melanocytic Skin Lesions through Histopathologic Transversal Sections
por: Braga, Juliana Casagrande Tavoloni, et al.
Publicado: (2013)

Neoadjuvant intraperitoneal chemotherapy followed by radical surgery and HIPEC in patients with very advanced gastric cancer and peritoneal metastases: report of an initial experience in a western single center
por: Fava, Bianca Escorel Costa, et al.
Publicado: (2018)

A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive disease
por: Ferreira, Elisa Napolitano, et al.
Publicado: (2016)

Disparities in Epidemiological Profile of Gastric Adenocarcinoma in Selected Cities of Brazil
por: Curado, Maria Paula, et al.
Publicado: (2019)

Moesin expression by tumor cells is an unfavorable prognostic biomarker for oral cancer
por: Barros, Francisco Bárbara Abreu, et al.
Publicado: (2018)

Historical Analysis of the Brazilian Cervical Cancer Screening Program from 2006 to 2013: A Time for Reflection
por: Costa, Ricardo Filipe Alves, et al.
Publicado: (2015)

Trend analysis of the quality indicators for the Brazilian cervical cancer screening programme by region and state from 2006 to 2013
por: Costa, Ricardo Filipe Alves, et al.
Publicado: (2018)

Evaluation of the Psychometric Properties of the Functional Assessment of Cancer Therapy-Cervix Questionnaire in Brazil
por: Fregnani, Cristiane Menezes Sirna, et al.
Publicado: (2013)

Methodological study to evaluate the psychometric properties of FACIT-CD in a sample of Brazilian women with cervical intraepithelial neoplasia
por: Fregnani, Cristiane Menezes Sirna, et al.
Publicado: (2017)

Digital photography in skin cancer screening by mobile units in remote areas of Brazil
por: Silveira, Carlos Eduardo Goulart, et al.
Publicado: (2014)

Expression of Cancer/Testis Antigens is Correlated with Improved Survival in Glioblastoma
por: Freitas, Marcelo Roberto Pereira, et al.
Publicado: (2013)

Expression of E-cadherin and β-catenin in basaloid and conventional squamous cell carcinoma of the oral cavity: are potential prognostic markers?
por: Hanemann, João Adolfo Costa, et al.
Publicado: (2014)

Inhibition of phosphatidylinositol 3‐kinase α (PI3Kα) prevents heterotopic ossification
por: Valer, José Antonio, et al.
Publicado: (2019)

Clinical factors related to severe enterocolitis after adjuvant CAPOX for colorectal cancer: a retrospective analysis
por: Felismino, Tiago Cordeiro, et al.
Publicado: (2020)

Biochemical and phylogenetic analyses of phosphatidylinositol production in Angomonas deanei, an endosymbiont-harboring trypanosomatid
por: de Azevedo-Martins, Allan C, et al.
Publicado: (2015)

Oral ulcerative lesions in a post-liver-transplantation patient
por: Nakamura, Gabriele Prospero, et al.
Publicado: (2019)

Phosphatidylinositol-4-Phosphate 5-Kinases and Phosphatidylinositol 4,5-Bisphosphate Synthesis in the Brain
por: Volpicelli-Daley, Laura A., et al.
Publicado: (2010)

Human papillomavirus genotypes distribution in 175 invasive cervical cancer cases from Brazil
por: de Oliveira, Cristina Mendes, et al.
Publicado: (2013)

The relationship between ezrin and podoplanin expressions in keratocystic odontogenic tumors
por: Oliveira, Denise Tostes, et al.
Publicado: (2014)

How is the transition away from fossil fuels doing, and how will the low-carbon future unfold?
por: Araújo, Ofélia Q. F., et al.
Publicado: (2021)

Sustainable and equitable decarbonization
por: Araújo, Ofélia Q. F., et al.
Publicado: (2022)

Nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children
por: Lopes, Márcia Marília Gomes Dantas, et al.
Publicado: (2015)

Antimicrobial Activity of an Fmoc-Plantaricin 149 Derivative Peptide against Multidrug-Resistant Bacteria
por: Righetto, Gabriela Marinho, et al.
Publicado: (2023)

Durable Response to Nivolumab in a Patient With Hepatic Sarcomatoid Carcinoma: Evolutive Characterization of Genomic and Immunohistochemical PD-L1 Expression Findings
por: Queiroz, Marcello M., et al.
Publicado: (2022)

Foxp3 expression is associated with aggressiveness in differentiated thyroid carcinomas
por: Cunha, Lucas Leite, et al.
Publicado: (2012)

The Use of (99m)Tc-Mononuclear Leukocyte Scintigraphy for Necrotizing External Otitis Diagnosis
por: de Souza, Sergio Augusto Lopes, et al.
Publicado: (2023)

Genotoxicity and pharmacokinetic characterization of Cereus jamacaru ethanolic extract in rats
por: de Medeiros, Iris Ucella, et al.
Publicado: (2019)

Reflectance confocal microscopy features of BRAF V600E mutated thin melanomas detected by immunohistochemistry
por: Urvanegia, Ana Claudia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mg9o1aqjppadridau59d59nku4