Cargando…

Polymorphism of MSH2 Gly322Asp and MLH1 –93G>A in non-familial colon cancer – a case-controlled study

INTRODUCTION: Our aim was to determine the effect of the single nucleotide polymorphisms (SNP) –93G>A of the MLH1 gene (rs1800734) and Gly322Asp of the MSH2 gene (rs4987188) on the risk of colon cancer (CC) and identify any relationship with clinical factors. MATERIAL AND METHODS: The study inclu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mik, Michal, Dziki, Lukasz, Malinowska, Katarzyna, Trzcinski, Radzislaw, Majsterek, Ireneusz, Dziki, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2017
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701696/ https://www.ncbi.nlm.nih.gov/pubmed/29181059 http://dx.doi.org/10.5114/aoms.2017.67024

Ejemplares similares

Right- and left-sided colon cancer – clinical and pathological differences of the disease entity in one organ
por: Mik, Michal, et al.
Publicado: (2016)

Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene
por: Dziki, L., et al.
Publicado: (2017)

Is there still a place for open surgery in the treatment strategy of rectal cancer?
por: Kawiński, Andrzej, et al.
Publicado: (2018)

Surgery in Jehovah's Witnesses – our experience
por: Trzciński, Radzisław, et al.
Publicado: (2015)

Preoperative oral antibiotics reduce infections after colorectal cancer surgery
por: Mik, Michal, et al.
Publicado: (2016)

Surgical treatment of haemorrhoidal disease – the current situation in Poland
por: Dziki, Lukasz, et al.
Publicado: (2016)

Association between SOD1, CAT, GSHPX1 polymorphisms and the risk of inflammatory bowel disease in the Polish population
por: Mrowicka, Malgorzata, et al.
Publicado: (2017)

Presacral tumors: diagnosis and treatment – a challenge for a surgeon
por: Dziki, Łukasz, et al.
Publicado: (2016)

The 116G > A MSH6 and IVS1-1121C > T PMS2 Genes Polymorphisms Modulate the Risk of the Sporadic Colorectal Cancer Development in Polish Population
por: Zelga, Piotr, et al.
Publicado: (2017)

Conventional and/or laparoscopic rectal cancer surgery: what is the current evidence?
por: Mik, Michal, et al.
Publicado: (2016)

The –553 T/A polymorphism in the promoter region of the FGF2 gene is associated with increased breast cancer risk in Polish women
por: Rykala, Jan, et al.
Publicado: (2014)

Mismatch Repair Proteins and Microsatellite Instability in Colorectal Carcinoma (MLH1, MSH2, MSH6 and PMS2): Histopathological and Immunohistochemical Study
por: Ismael, Nour El Hoda S., et al.
Publicado: (2017)

Incidence of colorectal cancer in Poland in 1999-2008
por: Klimczak, Alicja, et al.
Publicado: (2011)

Colorectal cancer mortality in Poland – analysis of regional variation
por: Klimczak, Alicja, et al.
Publicado: (2012)

Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis
por: Siwecka, Natalia, et al.
Publicado: (2019)

Gly322Asp and Asn127Ser single nucleotide polymorphisms (SNPs) of hMSH2 mismatch repair gene and the risk of triple-negative breast cancer in Polish women
por: Smolarz, Beata, et al.
Publicado: (2014)

MSH2 and MLH1 testing
por: Kurzawski, Grzegorz, et al.
Publicado: (2008)

Current concepts in the pathogenesis of cryptoglandular perianal fistula
por: Włodarczyk, Marcin, et al.
Publicado: (2021)

Expression of DNA repair proteins MSH2, MLH1 and MGMT in human benign and malignant thyroid lesions: An immunohistochemical study
por: Giaginis, Constantinos, et al.
Publicado: (2011)

Is suturing of the bladder defect in benign Enterovesical fistula necessary?
por: Dziki, Ł., et al.
Publicado: (2019)

The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers
por: Lawes, D A, et al.
Publicado: (2005)

Mlh1 interacts with both Msh2 and Msh6 for recruitment during mismatch repair
por: DuPrie, Matthew L., et al.
Publicado: (2022)

Protein–Phenolic Interactions as a Factor Affecting the Physicochemical Properties of White Bean Proteins
por: Sęczyk, Łukasz, et al.
Publicado: (2019)

Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients
por: Petersen, Sanne M, et al.
Publicado: (2013)

Prevalence and spectrum of MLH1, MSH2, and MSH6 pathogenic germline variants in Pakistani colorectal cancer patients
por: Rashid, Muhammad Usman, et al.
Publicado: (2019)

Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population
por: Kabzinski, J., et al.
Publicado: (2016)

Angiogenesis Markers Quantification in Breast Cancer and Their Correlation with Clinicopathological Prognostic Variables
por: Rykala, Jan, et al.
Publicado: (2011)

Population carrier frequency of hMSH2 and hMLH1 mutations
por: Dunlop, M G, et al.
Publicado: (2000)

Microsatellite Instability and Altered Expressions of MLH1 and MSH2 in Gastric Cancer
por: Haron, Nor Hasyimah, et al.
Publicado: (2019)

UMD-MLH1/MSH2/MSH6 databases: description and analysis of genetic variations in French Lynch syndrome families
por: Grandval, Philippe, et al.
Publicado: (2013)

An Evaluation of the Immunohistochemical Expression of Mismatch Repair Proteins (MSH2, MSH6, MLH1, and PMS2) in Prostate Adenocarcinoma
por: Javeed, Saira, et al.
Publicado: (2022)

Current Overview on the Use of Mesenchymal Stem Cells for Perianal Fistula Treatment in Patients with Crohn’s Disease
por: Włodarczyk, Marcin, et al.
Publicado: (2021)

Influence of Soluble Fiber as a Carrier on Antioxidant and Physical Properties of Powders Produced Based on the Spray Drying of Malvae arboreae flos Aqueous Extracts
por: Lisiecka, Katarzyna, et al.
Publicado: (2023)

Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells
por: Jin, Peng, et al.
Publicado: (2017)

Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2
por: Schrader, Carol E., et al.
Publicado: (2003)

Substantial unexplained variation in cancer risks for MLH1 and MSH2 mutation carriers
por: Dowty, JG, et al.
Publicado: (2012)

Novel Mutations in MLH1 and MSH2 Genes in Mexican Patients with Lynch Syndrome
por: Moreno-Ortiz, Jose Miguel, et al.
Publicado: (2016)

Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
por: Bologna-Molina, Ronell, et al.
Publicado: (2018)

Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
por: Ramsoekh, Dewkoemar, et al.
Publicado: (2009)

Germline MLH1, MSH2 and MSH6 variants in Brazilian patients with colorectal cancer and clinical features suggestive of Lynch Syndrome
por: Schneider, Nayê Balzan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tgkg4dd64krgqnacrrg5j5699e