Blockade of Inflammation and Apoptosis Pathways by siRNA Prolongs Cold Preservation Time and Protects Donor Hearts in a Porcine Model

In donor hearts from mini pigs, overtime cold preservation and ischemia-reperfusion injury cause poor graft quality and impaired heart function. Blockage of complement, apoptosis, and inflammation is considered a strategy for attenuating ischemia-reperfusion injury and protecting cardiac function. M...

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Detalles Bibliográficos
Autores principales: Wei, Jia, Chen, Shiyou, Xue, Song, Zhu, Qiangru, Liu, Sha, Cui, Li, Hua, Xiuguo, Wang, Yongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701800/
https://www.ncbi.nlm.nih.gov/pubmed/29246321
http://dx.doi.org/10.1016/j.omtn.2017.10.020

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