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A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms
Neuropathic pain develops when the somatosensory nervous system is affected by a lesion or disease. Diagnostic tests aimed at assessing somatosensory afferent pathway damage are therefore useful for diagnosing neuropathic pain. Neuropathic pain manifests with a range of different symptoms such as on...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Healthcare
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701892/ https://www.ncbi.nlm.nih.gov/pubmed/29178037 http://dx.doi.org/10.1007/s40122-017-0085-2 |
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author | Truini, Andrea |
author_facet | Truini, Andrea |
author_sort | Truini, Andrea |
collection | PubMed |
description | Neuropathic pain develops when the somatosensory nervous system is affected by a lesion or disease. Diagnostic tests aimed at assessing somatosensory afferent pathway damage are therefore useful for diagnosing neuropathic pain. Neuropathic pain manifests with a range of different symptoms such as ongoing burning pain, squeezing or pressure pain, paroxysmal electric shock-like sensations, stabbing pain, or mechanical dynamic allodynia. The various types of neuropathic pain are associated with different underlying nerve fiber abnormalities. This article summarizes the available methods of somatosensory afferent pathway assessment and discusses the potential pathophysiology underlying the most representative neuropathic pain types, i.e., ongoing burning pain, paroxysmal pain, and mechanical dynamic allodynia. Funding: Pfizer, Italy. |
format | Online Article Text |
id | pubmed-5701892 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Healthcare |
record_format | MEDLINE/PubMed |
spelling | pubmed-57018922017-12-05 A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms Truini, Andrea Pain Ther Review Neuropathic pain develops when the somatosensory nervous system is affected by a lesion or disease. Diagnostic tests aimed at assessing somatosensory afferent pathway damage are therefore useful for diagnosing neuropathic pain. Neuropathic pain manifests with a range of different symptoms such as ongoing burning pain, squeezing or pressure pain, paroxysmal electric shock-like sensations, stabbing pain, or mechanical dynamic allodynia. The various types of neuropathic pain are associated with different underlying nerve fiber abnormalities. This article summarizes the available methods of somatosensory afferent pathway assessment and discusses the potential pathophysiology underlying the most representative neuropathic pain types, i.e., ongoing burning pain, paroxysmal pain, and mechanical dynamic allodynia. Funding: Pfizer, Italy. Springer Healthcare 2017-11-24 2017-12 /pmc/articles/PMC5701892/ /pubmed/29178037 http://dx.doi.org/10.1007/s40122-017-0085-2 Text en © The Author(s) 2017 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Truini, Andrea A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title | A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title_full | A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title_fullStr | A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title_full_unstemmed | A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title_short | A Review of Neuropathic Pain: From Diagnostic Tests to Mechanisms |
title_sort | review of neuropathic pain: from diagnostic tests to mechanisms |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701892/ https://www.ncbi.nlm.nih.gov/pubmed/29178037 http://dx.doi.org/10.1007/s40122-017-0085-2 |
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