A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis

Neuropathic pain is characterized by both sensory and affective disturbances, supporting the notion that pain and mood disorders share common pathogenetic mechanisms. Moreover, biological and neuroimaging data show that common brain areas are involved in the modulation of painful and emotional exper...

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Detalles Bibliográficos
Autores principales: Torta, Riccardo, Ieraci, Valentina, Zizzi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701895/
https://www.ncbi.nlm.nih.gov/pubmed/29178035
http://dx.doi.org/10.1007/s40122-017-0088-z
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author Torta, Riccardo
Ieraci, Valentina
Zizzi, Francesca
author_facet Torta, Riccardo
Ieraci, Valentina
Zizzi, Francesca
author_sort Torta, Riccardo
collection PubMed
description Neuropathic pain is characterized by both sensory and affective disturbances, supporting the notion that pain and mood disorders share common pathogenetic mechanisms. Moreover, biological and neuroimaging data show that common brain areas are involved in the modulation of painful and emotional experiences. Improved understanding of the molecular mechanisms underlying the role of neuroinflammation in regulation of affective behavior in neuropathic pain states is important for the development of novel therapeutic strategies. Psychological issues must be considered a factor influencing treatment and outcome in patients with neuropathic pain. Funding: Pfizer, Italy.
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spelling pubmed-57018952017-12-05 A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis Torta, Riccardo Ieraci, Valentina Zizzi, Francesca Pain Ther Review Neuropathic pain is characterized by both sensory and affective disturbances, supporting the notion that pain and mood disorders share common pathogenetic mechanisms. Moreover, biological and neuroimaging data show that common brain areas are involved in the modulation of painful and emotional experiences. Improved understanding of the molecular mechanisms underlying the role of neuroinflammation in regulation of affective behavior in neuropathic pain states is important for the development of novel therapeutic strategies. Psychological issues must be considered a factor influencing treatment and outcome in patients with neuropathic pain. Funding: Pfizer, Italy. Springer Healthcare 2017-11-24 2017-12 /pmc/articles/PMC5701895/ /pubmed/29178035 http://dx.doi.org/10.1007/s40122-017-0088-z Text en © The Author(s) 2017 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Torta, Riccardo
Ieraci, Valentina
Zizzi, Francesca
A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title_full A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title_fullStr A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title_full_unstemmed A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title_short A Review of the Emotional Aspects of Neuropathic Pain: From Comorbidity to Co-Pathogenesis
title_sort review of the emotional aspects of neuropathic pain: from comorbidity to co-pathogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701895/
https://www.ncbi.nlm.nih.gov/pubmed/29178035
http://dx.doi.org/10.1007/s40122-017-0088-z
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