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Mesenchymal Stem Cells Induce Expression of CD73 in Human Monocytes In Vitro and in a Swine Model of Myocardial Infarction In Vivo

The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti-inflammatory regulation by Ado. Mesenchymal stem ce...

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Detalles Bibliográficos
Autores principales:	Monguió-Tortajada, Marta, Roura, Santiago, Gálvez-Montón, Carolina, Franquesa, Marcella, Bayes-Genis, Antoni, Borràs, Francesc E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701925/ https://www.ncbi.nlm.nih.gov/pubmed/29209319 http://dx.doi.org/10.3389/fimmu.2017.01577

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