Complement Receptor 3 Has Negative Impact on Tumor Surveillance through Suppression of Natural Killer Cell Function

Complement receptor 3 (CR3) is expressed abundantly on natural killer (NK) cells; however, whether it plays roles in NK cell-dependent tumor surveillance is largely unknown. Here, we show that CR3 is an important negative regulator of NK cell function, which has negative impact on tumor surveillance...

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Detalles Bibliográficos
Autores principales: Liu, Cheng-Fei, Min, Xiao-Yun, Wang, Naiyin, Wang, Jia-Xing, Ma, Ning, Dong, Xia, Zhang, Bing, Wu, Weiju, Li, Zong-Fang, Zhou, Wuding, Li, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702005/
https://www.ncbi.nlm.nih.gov/pubmed/29209332
http://dx.doi.org/10.3389/fimmu.2017.01602

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