Multiple pathways facilitate the biogenesis of mammalian tail-anchored proteins

Tail-anchored (TA) proteins are transmembrane proteins with a single C-terminal transmembrane domain, which functions as both their subcellular targeting signal and membrane anchor. We show that knockout of TRC40 in cultured human cells has a relatively minor effect on endogenous TA proteins, despit...

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Detalles Bibliográficos
Autores principales: Casson, Joseph, McKenna, Michael, Haßdenteufel, Sarah, Aviram, Naama, Zimmerman, Richard, High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702047/
https://www.ncbi.nlm.nih.gov/pubmed/29021347
http://dx.doi.org/10.1242/jcs.207829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702047/
https://www.ncbi.nlm.nih.gov/pubmed/29021347
http://dx.doi.org/10.1242/jcs.207829

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