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Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation

BACKGROUND: Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction osteogenesis. The objective of this study is to invest...

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Autores principales: Zhang, Qun, Zhang, Wei, Zhang, Zhuo, Zhang, Licheng, Chen, Hua, Hao, Ming, Deng, Junhao, Tang, Peifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702156/
https://www.ncbi.nlm.nih.gov/pubmed/29178906
http://dx.doi.org/10.1186/s13018-017-0684-y
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author Zhang, Qun
Zhang, Wei
Zhang, Zhuo
Zhang, Licheng
Chen, Hua
Hao, Ming
Deng, Junhao
Tang, Peifu
author_facet Zhang, Qun
Zhang, Wei
Zhang, Zhuo
Zhang, Licheng
Chen, Hua
Hao, Ming
Deng, Junhao
Tang, Peifu
author_sort Zhang, Qun
collection PubMed
description BACKGROUND: Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction osteogenesis. The objective of this study is to investigate the outcomes of segmental femoral defects treated with monolateral external fixation using the distraction osteogenesis. METHODS: We retrospectively analyzed patients with femoral nonunion with segmental bone defects (> 6 cm) between January 2010 and January 2014 in our single trauma center. All patients were treated by distraction osteogenesis with monolateral external fixation. All surgeries were performed by the same surgeon. Bone union, duration of distraction osteogenesis in days, time to consolidation in months, external fixation index (EFI), complications, and additional surgical interventions were recorded postoperatively. The modified Application of Methods of Illizarov (ASAMI) criteria were used to evaluate the operative effectiveness. RESULTS: Forty-one patients were enrolled in this study for analysis. The length of the bone defect ranged from 6 to 17 cm. All patients eventually achieved healing, and no patient experienced recurrence of infection or newly developed infection. The average time needed for healing was 13 months. In terms of the incidence of complications, 3 cases axial deviations, 5 cases docking site nonunion, 23 cases pin-tract infection, 14 cases knee joint stiffness or their joint mobility declined, 2 cases osteogenesis insufficient in the distraction area,1 case refracture, and 2 cases loose external fixation pins. In terms of the evaluations of fracture healing and function, 30 patients excellent, 6 patients good, 5 patients fair, and 0 patient poor. In terms of postoperative function evaluations, 21 patients excellent, 9 patients good, 7 patients fair, and 4 patients poor. CONCLUSION: For patients with femoral nonunion with large segmental bone defects, the monolateral external fixation can provide effective stability, improve compliance, and reduce complications. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13018-017-0684-y) contains supplementary material, which is available to authorized users.
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spelling pubmed-57021562017-12-04 Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation Zhang, Qun Zhang, Wei Zhang, Zhuo Zhang, Licheng Chen, Hua Hao, Ming Deng, Junhao Tang, Peifu J Orthop Surg Res Research Article BACKGROUND: Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction osteogenesis. The objective of this study is to investigate the outcomes of segmental femoral defects treated with monolateral external fixation using the distraction osteogenesis. METHODS: We retrospectively analyzed patients with femoral nonunion with segmental bone defects (> 6 cm) between January 2010 and January 2014 in our single trauma center. All patients were treated by distraction osteogenesis with monolateral external fixation. All surgeries were performed by the same surgeon. Bone union, duration of distraction osteogenesis in days, time to consolidation in months, external fixation index (EFI), complications, and additional surgical interventions were recorded postoperatively. The modified Application of Methods of Illizarov (ASAMI) criteria were used to evaluate the operative effectiveness. RESULTS: Forty-one patients were enrolled in this study for analysis. The length of the bone defect ranged from 6 to 17 cm. All patients eventually achieved healing, and no patient experienced recurrence of infection or newly developed infection. The average time needed for healing was 13 months. In terms of the incidence of complications, 3 cases axial deviations, 5 cases docking site nonunion, 23 cases pin-tract infection, 14 cases knee joint stiffness or their joint mobility declined, 2 cases osteogenesis insufficient in the distraction area,1 case refracture, and 2 cases loose external fixation pins. In terms of the evaluations of fracture healing and function, 30 patients excellent, 6 patients good, 5 patients fair, and 0 patient poor. In terms of postoperative function evaluations, 21 patients excellent, 9 patients good, 7 patients fair, and 4 patients poor. CONCLUSION: For patients with femoral nonunion with large segmental bone defects, the monolateral external fixation can provide effective stability, improve compliance, and reduce complications. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13018-017-0684-y) contains supplementary material, which is available to authorized users. BioMed Central 2017-11-25 /pmc/articles/PMC5702156/ /pubmed/29178906 http://dx.doi.org/10.1186/s13018-017-0684-y Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Zhang, Qun
Zhang, Wei
Zhang, Zhuo
Zhang, Licheng
Chen, Hua
Hao, Ming
Deng, Junhao
Tang, Peifu
Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title_full Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title_fullStr Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title_full_unstemmed Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title_short Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
title_sort femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702156/
https://www.ncbi.nlm.nih.gov/pubmed/29178906
http://dx.doi.org/10.1186/s13018-017-0684-y
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