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Diallyl disulphide inhibits apolipoprotein(a) expression in HepG2 cells through the MEK1-ERK1/2-ELK-1 pathway

BACKGROUND: Lipoprotein(a) [LP(a)] is implicated as a common and independent risk factor for cardiovascular diseases. The therapeutic options currently available for reducing plasma LP(a) concentrations are limited. Diallyl disulphide (DADS), the main component of garlic, regulates lipid metabolism...

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Detalles Bibliográficos
Autores principales:	Ma, Xiaofeng, Liu, Yami, Tan, Yanmei, Qu, Kai, He, Xinglan, Zhang, Hai, Wang, Zuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702159/ https://www.ncbi.nlm.nih.gov/pubmed/29178936 http://dx.doi.org/10.1186/s12944-017-0616-1

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