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MiR-139 suppresses β-casein synthesis and proliferation in bovine mammary epithelial cells by targeting the GHR and IGF1R signaling pathways

BACKGROUND: MicroRNAs have important roles in many biological processes. However, the role of miR-139 in healthy mammary gland remains unclear. The objective of this study was to investigate the effects of miR-139 on lactation in dairy cows. RESULTS: Here, we found that miR-139 was down-regulated in...

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Detalles Bibliográficos
Autores principales: Cui, Yingjun, Sun, Xia, Jin, Lianfeng, Yu, Guangpu, Li, Qingzhang, Gao, Xuejun, Ao, Jinxia, Wang, Chunmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702184/
https://www.ncbi.nlm.nih.gov/pubmed/29178948
http://dx.doi.org/10.1186/s12917-017-1267-1