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Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid

BACKGROUND: Streptomyces clavuligerus ATCC 27064, the industrial producer of the β-lactamase inhibitor clavulanic acid, carries 49 putative secondary metabolite gene clusters. These secondary metabolite gene clusters are distributed between its linear chromosome and the 1.8 Mb-plasmid pSCL4, a rich...

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Detalles Bibliográficos
Autores principales:	Álvarez-Álvarez, Rubén, Martínez-Burgo, Yolanda, Rodríguez-García, Antonio, Liras, Paloma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702194/ https://www.ncbi.nlm.nih.gov/pubmed/29178826 http://dx.doi.org/10.1186/s12864-017-4289-y

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