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An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial

BACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroquinolones as part of the regimen has not been defined. M...

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Detalles Bibliográficos
Autores principales:	Bouton, Tara C., Phillips, Patrick P. J., Mitnick, Carole D., Peloquin, Charles A., Eisenach, Kathleen, Patientia, Ramonde F., Lecca, Leonid, Gotuzzo, Eduardo, Gandhi, Neel R., Butler, Donna, Diacon, Andreas H., Martel, Bruno, Santillan, Juan, Hunt, Kathleen Robergeau, Vargas, Dante, von Groote-Bidlingmaier, Florian, Seas, Carlos, Dianis, Nancy, Moreno-Martinez, Antonio, Horsburgh, C. Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702225/ https://www.ncbi.nlm.nih.gov/pubmed/29178937 http://dx.doi.org/10.1186/s13063-017-2292-x

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