Cargando…

Absence of the Non-Signalling Chemerin Receptor CCRL2 Exacerbates Acute Inflammatory Responses In Vivo

Chemerin is a chemotactic protein that induces migration of several immune cells including macrophages, immature dendritic cells, and NK cells. Chemerin binds to three G protein-coupled receptors (GPCRs), including CCRL2. The exact function of CCRL2 remains unclear. CCRL2 expression is rapidly upreg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Regan-Komito, Daniel, Valaris, Sophia, Kapellos, Theodore S., Recio, Carlota, Taylor, Lewis, Greaves, David R., Iqbal, Asif J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702352/ https://www.ncbi.nlm.nih.gov/pubmed/29209334 http://dx.doi.org/10.3389/fimmu.2017.01621

Ejemplares similares

Cannabinoid receptor 2 deficiency exacerbates inflammation and neutrophil recruitment
por: Kapellos, Theodore S., et al.
Publicado: (2019)

Cannabinoid Receptor 2 Modulates Neutrophil Recruitment in a Murine Model of Endotoxemia
por: Kapellos, Theodore S., et al.
Publicado: (2017)

Exploring CCRL2 chemerin binding using accelerated molecular dynamics
por: Bufano, Marianna, et al.
Publicado: (2022)

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2
por: De Henau, Olivier, et al.
Publicado: (2016)

Expression of CCRL2 Inhibits Tumor Growth by Concentrating Chemerin and Inhibiting Neoangiogenesis
por: Al Delbany, Diana, et al.
Publicado: (2021)

A Real Time Chemotaxis Assay Unveils Unique Migratory Profiles amongst Different Primary Murine Macrophages
por: Iqbal, Asif J., et al.
Publicado: (2013)

Mast cell–expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis
por: Zabel, Brian A., et al.
Publicado: (2008)

Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis
por: McNeill, Eileen, et al.
Publicado: (2014)

A novel real time imaging platform to quantify macrophage phagocytosis
por: Kapellos, Theodore S., et al.
Publicado: (2016)

Editorial: Molecular mechanisms regulating phenotypic heterogeneity in human inflammatory diseases
por: Kapellos, Theodore S., et al.
Publicado: (2023)

The Atypical Receptor CCRL2 (C-C Chemokine Receptor-Like 2) Does Not Act As a Decoy Receptor in Endothelial Cells
por: Mazzotti, Chiara, et al.
Publicado: (2017)

Molecular Basis for CCRL2 Regulation of Leukocyte Migration
por: Schioppa, Tiziana, et al.
Publicado: (2020)

Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation
por: Kapellos, Theodore S., et al.
Publicado: (2016)

OsCCRL1 is Essential for Phenylpropanoid Metabolism in Rice Anthers
por: Zhang, Lisha, et al.
Publicado: (2023)

Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease
por: Godlewska, Urszula, et al.
Publicado: (2017)

Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB(2) Receptor
por: Taylor, Lewis, et al.
Publicado: (2015)

Chemerin promotes angiogenesis in vivo
por: Nakamura, Nobuhisa, et al.
Publicado: (2018)

Atypical chemokine receptor CCRL2 is overexpressed in prostate cancer cells
por: Reyes, Niradiz, et al.
Publicado: (2019)

CCRL2 Modulates Physiological and Pathological Angiogenesis During Retinal Development
por: Ben Dhaou, Cyrine, et al.
Publicado: (2021)

Mechanisms and Functions of Chemerin in Cancer: Potential Roles in Therapeutic Intervention
por: Shin, Woo Jae, et al.
Publicado: (2018)

Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages
por: Recio, Carlota, et al.
Publicado: (2018)

Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases
por: Kapellos, Theodore S., et al.
Publicado: (2019)

Chemerin Suppresses Breast Cancer Growth by Recruiting Immune Effector Cells Into the Tumor Microenvironment
por: Pachynski, Russell K., et al.
Publicado: (2019)

Chemerin plasma levels are increased in COVID-19 patients and are an independent risk factor of mortality
por: Lavis, Philomène, et al.
Publicado: (2022)

The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids
por: Bartosik, Tina J., et al.
Publicado: (2023)

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia
por: Karantanos, Theodoros, et al.
Publicado: (2022)

CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine
por: Karantanos, Theodoros, et al.
Publicado: (2022)

From cell surface to nucleus: CCRL2 regulates response to hypomethylating agents in myelodysplastic syndromes
por: Saygin, Caner
Publicado: (2023)

Loss of chemerin triggers bone remodeling in vivo and in vitro
por: Han, Long, et al.
Publicado: (2021)

Chemerin and Cancer
por: Treeck, Oliver, et al.
Publicado: (2019)

Ccrl2 deficiency deteriorates obesity and insulin resistance through increasing adipose tissue macrophages infiltration
por: Xu, Min, et al.
Publicado: (2020)

Chemerin contributes to in vivo adipogenesis in a location-specific manner
por: Ferland, David J., et al.
Publicado: (2020)

Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization
por: Ma, Wenxin, et al.
Publicado: (2019)

RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling
por: Patel, Jyoti, et al.
Publicado: (2015)

Chemerin Signaling in Cancer
por: Treeck, Oliver, et al.
Publicado: (2020)

Regulatory effect of chemerin and therapeutic efficacy of chemerin-9 in pancreatogenic diabetes mellitus
por: Tu, Jianfeng, et al.
Publicado: (2020)

The interplay of galectins-1, -3, and -9 in the immune-inflammatory response underlying cardiovascular and metabolic disease
por: Mansour, Adel Abo, et al.
Publicado: (2022)

Comparative modeling of CCRL1, a key protein in masked immune diseases and virtual screening for finding inhibitor of this protein
por: Behjati, Mohaddeseh, et al.
Publicado: (2012)

Role of Exonic Variation in Chemokine Receptor Genes on AIDS: CCRL2 F167Y Association with Pneumocystis Pneumonia
por: An, Ping, et al.
Publicado: (2011)

Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo
por: Iqbal, Asif J, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n9882r2gfhi9c6jmh8r75ecfbh