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Phylogenetic Diversity in Core Region of Hepatitis C Virus Genotype 1a as a Factor Associated with Fibrosis Severity in HIV-1-Coinfected Patients

High hepatitis C virus (HCV) genetic diversity impacts infectivity/pathogenicity, influencing chronic liver disease progression associated with fibrosis degrees and hepatocellular carcinoma. HCV core protein is crucial in cell-growth regulation and host-gene expression. Liver fibrosis is accelerated...

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Detalles Bibliográficos
Autores principales:	Parra, Micaela, Laufer, Natalia, Manrique, Julieta M., Jones, Leandro R., Quarleri, Jorge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702417/ https://www.ncbi.nlm.nih.gov/pubmed/29259976 http://dx.doi.org/10.1155/2017/1728456

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