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Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis

The combination of alteplase, a recombinant tissue plasminogen activator, and edaravone, an antioxidant, reportedly enhances recanalization after acute ischemic stroke. We examined the influence of edaravone on the thrombolytic efficacy of alteplase by measuring thrombolysis using a newly developed...

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Detalles Bibliográficos
Autores principales: Kikuchi, Kiyoshi, Setoyama, Kentaro, Kawahara, Ko-ichi, Nagasato, Tomoka, Terashi, Takuto, Ueda, Koki, Nakanishi, Kazuki, Otsuka, Shotaro, Miura, Naoki, Sameshima, Hisayo, Hosokawa, Kazuya, Harada, Yoichiro, Shrestha, Binita, Yamamoto, Mika, Morimoto-Yamashita, Yoko, Kikuchi, Haruna, Kiyama, Ryoji, Kamikokuryo, Chinatsu, Tancharoen, Salunya, Sakakima, Harutoshi, Morioka, Motohiro, Tanaka, Eiichiro, Ito, Takashi, Maruyama, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702421/
https://www.ncbi.nlm.nih.gov/pubmed/29259732
http://dx.doi.org/10.1155/2017/6873281

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