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Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome

Removal of internal transcribed spacer 2 (ITS2) from pre-ribosomal RNA is essential to make functional ribosomes. This complicated processing reaction begins with a single endonucleolytic cleavage followed by exonucleolytic trimming at both new cleavage sites to generate mature 5.8S and 25S rRNA. We...

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Detalles Bibliográficos
Autores principales:	Fromm, Lisa, Falk, Sebastian, Flemming, Dirk, Schuller, Jan Michael, Thoms, Matthias, Conti, Elena, Hurt, Ed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702609/ https://www.ncbi.nlm.nih.gov/pubmed/29176610 http://dx.doi.org/10.1038/s41467-017-01786-9

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