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Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2

Break-induced replication (BIR) is a DNA double-strand break repair pathway that leads to genomic instabilities similar to those observed in cancer. BIR proceeds by a migrating bubble where asynchrony between leading and lagging strand synthesis leads to accumulation of long single-stranded DNA (ssD...

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Detalles Bibliográficos
Autores principales:	Elango, Rajula, Sheng, Ziwei, Jackson, Jessica, DeCata, Jenna, Ibrahim, Younis, Pham, Nhung T., Liang, Diana H., Sakofsky, Cynthia J., Vindigni, Alessandro, Lobachev, Kirill S., Ira, Grzegorz, Malkova, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702615/ https://www.ncbi.nlm.nih.gov/pubmed/29176630 http://dx.doi.org/10.1038/s41467-017-01987-2

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