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Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3

Signal transducer and activator of transcription 3(STAT3) is an emerging target for cancer therapy. In this study, we identify Toosendanin (TSN) is an effective inhibitor of STAT3, leading to the impediment of various oncogenic processes in osteosarcoma. TSN selectively inactivates phospho-STAT3 (Ty...

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Detalles Bibliográficos
Autores principales:	Zhang, T, Li, J, Yin, F, Lin, B, Wang, Z, Xu, J, Wang, H, Zuo, D, Wang, G, Hua, Y, Cai, Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702716/ https://www.ncbi.nlm.nih.gov/pubmed/28783167 http://dx.doi.org/10.1038/onc.2017.270

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