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Improving Realism in Clinical Trial Simulations via Real‐World Data
Simulation validity depends on how well sampling distributions used reflect real‐patient characteristics, such as drug adherence, disease progression, and pharmacologic handling in the body. We challenge the current use of growth charts from nondisease‐specific pediatrics in simulations for drug dev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702896/ https://www.ncbi.nlm.nih.gov/pubmed/28925064 http://dx.doi.org/10.1002/psp4.12232 |