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mTOR-Dependent Cell Proliferation in the Brain
The mammalian Target of Rapamycin (mTOR) is a molecular complex equipped with kinase activity which controls cell viability being key in the PI3K/PTEN/Akt pathway. mTOR acts by integrating a number of environmental stimuli to regulate cell growth, proliferation, autophagy, and protein synthesis. The...
Autores principales: | Ryskalin, Larisa, Lazzeri, Gloria, Flaibani, Marina, Biagioni, Francesca, Gambardella, Stefano, Frati, Alessandro, Fornai, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702949/ https://www.ncbi.nlm.nih.gov/pubmed/29259984 http://dx.doi.org/10.1155/2017/7082696 |
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