Cargando…
Anticancer effect of dentatin and dentatin-hydroxypropyl-β-cyclodextrin complex on human colon cancer (HT-29) cell line
INTRODUCTION: Dentatin (DEN) (5-methoxy-2, 2-dimethyl-10-(1, 1-dimethyl-2propenyl) dipyran-2-one), a natural compound present in the roots of Clausena excavata Burm f, possesses pro-apoptotic and antiproliferative effects in various cancer cells. Because of its hydrophobicity, it is believed that it...
Autores principales: | AL-Abboodi, Ashwaq Shakir, Rasedee, Abdullah, Abdul, Ahmad Bustamam, Taufiq-Yap, Yun Hin, Alkaby, Wafaa Abd Alwahed, Ghaji, Mostafa Saddam, Waziri, Peter M, Al-Qubaisi, Mothanna Sadiq |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703156/ https://www.ncbi.nlm.nih.gov/pubmed/29200826 http://dx.doi.org/10.2147/DDDT.S147626 |
Ejemplares similares
-
Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-β-Cyclodextrin (DEN-HPβCD)
por: Ashwaq, Al-Abboodi Shakir, et al.
Publicado: (2016) -
Inclusion complex of clausenidin with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-colon cancer activity
por: Al-Abboodi, Ashwaq Shakir, et al.
Publicado: (2021) -
Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition
por: Arbab, Ismail Adam, et al.
Publicado: (2012) -
Simultaneous determination of nine analytes in Clausena harmandiana Pierre. by new developed high-performance liquid chromatography method and the influence of locations in Thailand on level of nordentatin and dentatin
por: Wangboonskul, Jinda, et al.
Publicado: (2015) -
Preparation, characterization, in vitro drug release and anti-inflammatory of thymoquinone-loaded chitosan nanocomposite
por: Al-Qubaisi, Mothanna Sadiq, et al.
Publicado: (2022)