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DGR mutagenic transposition occurs via hypermutagenic reverse transcription primed by nicked template RNA
Diversity-generating retroelements (DGRs) are molecular evolution machines that facilitate microbial adaptation to environmental changes. Hypervariation occurs via a mutagenic retrotransposition process from a template repeat (TR) to a variable repeat (VR) that results in adenine-to-random nucleotid...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703328/ https://www.ncbi.nlm.nih.gov/pubmed/29109248 http://dx.doi.org/10.1073/pnas.1715952114 |