Targeting muscle stem cell intrinsic defects to treat Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a genetic disease characterised by skeletal muscle degeneration and progressive muscle wasting, which is caused by loss-of-function mutations in the DMD gene that encodes for the protein dystrophin. Dystrophin has critical roles in myofiber stability and integrit...

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Detalles Bibliográficos
Autores principales: Dumont, Nicolas A, Rudnicki, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703417/
https://www.ncbi.nlm.nih.gov/pubmed/29188075
http://dx.doi.org/10.1038/npjregenmed.2016.6

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