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Neurturin overexpression in dopaminergic neurons induces presynaptic and postsynaptic structural changes in rats with chronic 6-hydroxydopamine lesion

The structural effect of neurturin (NRTN) on the nigrostriatal dopaminergic system in animals remains unknown, although NRTN has been shown to be effective in Parkinson’s disease animal models. Herein, we aimed to demonstrate that NRTN overexpression in dopaminergic neurons stimulates both neurite o...

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Detalles Bibliográficos
Autores principales: Reyes-Corona, David, Vázquez-Hernández, Nallely, Escobedo, Lourdes, Orozco-Barrios, Carlos E., Ayala-Davila, Jose, Moreno, Mario Gil, Amaro-Lara, Miriam E., Flores-Martinez, Yazmin M., Espadas-Alvarez, Armando J., Fernandez-Parrilla, Manuel A., Gonzalez-Barrios, Juan A., Gutierrez-Castillo, ME, González-Burgos, Ignacio, Martinez-Fong, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703459/
https://www.ncbi.nlm.nih.gov/pubmed/29176874
http://dx.doi.org/10.1371/journal.pone.0188239