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T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells

HLA-E is a non-conventional MHC Class I molecule that has been recently demonstrated to present pathogen-derived ligands, resulting in the TCR-dependent activation of αβ CD8(+) T cells. The goal of this study was to characterize the ligandome displayed by HLA-E following infection with Mycobacterium...

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Detalles Bibliográficos
Autores principales: McMurtrey, Curtis, Harriff, Melanie J., Swarbrick, Gwendolyn M., Duncan, Amanda, Cansler, Meghan, Null, Megan, Bardet, Wilfried, Jackson, Kenneth W., Lewinsohn, Deborah A., Hildebrand, William, Lewinsohn, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703486/
https://www.ncbi.nlm.nih.gov/pubmed/29176828
http://dx.doi.org/10.1371/journal.pone.0188288