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T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells
HLA-E is a non-conventional MHC Class I molecule that has been recently demonstrated to present pathogen-derived ligands, resulting in the TCR-dependent activation of αβ CD8(+) T cells. The goal of this study was to characterize the ligandome displayed by HLA-E following infection with Mycobacterium...
Autores principales: | McMurtrey, Curtis, Harriff, Melanie J., Swarbrick, Gwendolyn M., Duncan, Amanda, Cansler, Meghan, Null, Megan, Bardet, Wilfried, Jackson, Kenneth W., Lewinsohn, Deborah A., Hildebrand, William, Lewinsohn, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703486/ https://www.ncbi.nlm.nih.gov/pubmed/29176828 http://dx.doi.org/10.1371/journal.pone.0188288 |
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