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Automated visualization of rule-based models
Frameworks such as BioNetGen, Kappa and Simmune use “reaction rules” to specify biochemical interactions compactly, where each rule specifies a mechanism such as binding or phosphorylation and its structural requirements. Current rule-based models of signaling pathways have tens to hundreds of rules...
Autores principales: | Sekar, John Arul Prakash, Tapia, Jose-Juan, Faeder, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703574/ https://www.ncbi.nlm.nih.gov/pubmed/29131816 http://dx.doi.org/10.1371/journal.pcbi.1005857 |
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