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Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

Phase transitions of linear multivalent proteins control the reversible formation of many intracellular membraneless bodies. Specific non-covalent crosslinks involving domains/motifs lead to system-spanning networks referred to as gels. Gelation transitions can occur with or without phase separation...

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Detalles Bibliográficos
Autores principales:	Harmon, Tyler S, Holehouse, Alex S, Rosen, Michael K, Pappu, Rohit V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703641/ https://www.ncbi.nlm.nih.gov/pubmed/29091028 http://dx.doi.org/10.7554/eLife.30294

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